毛剑，男，博士，1988年11月出生于天津

         杭州师范大学医学院副研究员

联系方式

杭州师范大学医学院衰老研究所

电话: 0571-2886-1641

Email: maojian@hznu.edu.cn

教育背景

博士：细胞生物学，南开大学，2017

学士：生物技术，南开大学，2011

专业和研究方向

所从事的专业为细胞生物学，研究方向为内源性逆转录病毒在衰老与癌变中的作用及机制。

主要工作简历

2011年毕业于南开大学生命科学学院生物技术专业，获理学学士学位，2017年毕业于南开大学生命科学学院细胞生物学专业，获理学博士学位。现为杭州师范大学医学院衰老研究所副研究员。在Stem cell reports、Stem cells and development等期刊发表多篇研究论文，参与国家重点基础研究发展计划（973计划）、国家自然科学基金重点项目、面上项目等多个项目的研究。

代表性论著(#co-first authors, *corresponding authors)

[1] Mao J, Zhang Q, Deng W, Wang H, Liu K, Fu H, Zhao Q, Wang X, Liu L^* (2017) Epigenetic Modifiers Facilitate Induction and Pluripotency of Porcine iPSCs. Stem Cell Reports. 10;8(1):11-20.

[2] Mao J, Zhang Q, Ye X, Liu K, Liu L^* (2014) Efficient induction of pluripotent stem cells from granulosa cells by Oct4 and Sox2. Stem Cells Dev. 23(7):779-89.

[3] Mao J, Liu L^* (2016) Generation of iPS Cells from Granulosa Cells. Methods Mol Biol. 1357:451-64.

[4] Liu K^#, Mao J^#, Song L, Fan A, Zhang S, Wang J, Fan N, Liu N, Ye X, Fu H, Zhou Z, Wang Y, Wei H, Liu Z, Li Z, Lai L, Wang X^*, Liu L^* (2017) DNA repair and replication links to pluripotency and differentiation capacity of pig iPS cells. PLoS One. 12(3):e0173047.

[5] Zhang Q, Liu N, Bai J, Zhou Q, Mao J, Xu L, Liu J, Wei H, Ren C, Wu X, Wang M, Zhao B^*, Cong YS^* (2020) Human telomerase reverse transcriptase is a novel target of Hippo-YAP pathway. FASEB J. 34(3):4178-4188.

[6] Zhang Q, Mao J, Zhang X, Fu H, Xia S, Yin Z, Liu L^* (2016) Role of Jnk1 in development of neural precursors revealed by iPSC modeling. Oncotarget. 7(38):60919-60928.

[7] Zhang Q, Dan J, Wang H, Guo R, Mao J, Fu H, Wei X, Liu L^* (2016) Tcstv1 and Tcstv3 elongate telomeres of mouse ES cells. Sci Rep. 6:19852.

[8] Kong Q^#, Ji G^#, Xie B, Li J, Mao J, Wang J, Liu S, Liu L^*, Liu Z^* (2014) Telomere elongation facilitated by trichostatin a in cloned embryos and pigs by somatic cell nuclear transfer. Stem Cell Rev Rep. 10(3):399-407.

[9] Yuan J^#, Zhang D^#, Wang L^#, Liu M, Mao J, Yin Y, Ye X, Liu N, Han J, Gao Y, Cheng T, Keefe DL, Liu L^* (2013) No evidence for neo-oogenesis may link to ovarian senescence in adult monkey. Stem Cells. 31(11):2538-50.

[10] Liu K, Ji G, Mao J, Liu M, Wang L, Chen C, Liu L^* (2012) Generation of porcine-induced pluripotent stem cells by using OCT4 and KLF4 porcine factors. Cell Reprogram. 14(6):505-13.